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The different drug types include the following: Depressants. Drugs that suppress or slow the activity of the brain and nerves, acting directly on the central nervous system to create a calming or sedating effect. 'prescription drugs are categorized in the united states through the controlled substances act into five schedules, or classes, based upon the governments perspective of their potential abuse.' SCHEDULE 1 (CLASS I) DRUGS are illegal because they have high abuse potential, no medical use, and severe safety concerns; for example, narcotics such.